Neurofibromatosis case essay

A combined one-stage transabdominal and transgluteal approach allows safe resection of selected benign but extensive sciatic notch tumors. Resection of benign sciatic notch dumbbell-shaped tumors The operative management of combined intrapelvic and extrapelvic sciatic notch dumbbell-shaped tumors is challenging.

In two patients with bilateral symptoms and extensive tumor burden, serial MR images showed that innumerable tumors directly involved the entire cross-sectional area of the sciatic nerves and extended longitudinally to the lumbosacral plexuses.

The authors believe that as this imaging technology advances, it will provide surgeons with a method to predict definitively which sciatic notch tumors displace rather than directly involve the sciatic nerve, and therefore indicate which tumors can be resected safely and completely.

The relatively rare occurrence of these tumors and the varied extent of disease have made it difficult for surgeons to establish definitive surgical indications or predict favorable neurological outcomes based on preoperative imaging data. The relatively rare occurrence of these tumors and the varied extent of disease have made it difficult for surgeons to High-resolution MR imaging is a useful tool in the management of these tumors because it allows the surgeon to visualize the anatomical relationships of the tumor to the sciatic nerve.


These two patients were treated pharmacologically and advised to monitor their tumor status over the course of their lifetimes in case of malignant transformation of the tumor. After high-resolution magnetic resonance MR imaging demonstrated that the extensive tumors were separate from the sciatic nerve and the lumbosacral plexus, however, these patients underwent a combined one-stage transabdominal and posterior transgluteal complete resection.

Normal neurological status was maintained postoperatively in these three patients, and after more than 1 year of postoperative follow up, there were no tumor recurrences. These tumors in three patients with unilateral leg symptoms were considered unresectable by other neurosurgeons because of presumed direct intrinsic neural involvement.

In the past 3 years, the authors treated five patients presenting with radiating leg pain as a result of benign sciatic notch dumbbell-shaped tumors.

Tumor debulking or resection in these patients would have resulted in neurological deficits and would not have addressed their neuropathic pain, and therefore no surgery was performed.Neurofibromatosis Case Report. Print Reference this. Disclaimer: This work has been submitted by a student.

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If you are the original writer of this essay and no longer wish to have the essay published on the UK Essays website then please click on the link below. We describe the case of a patient with neurofibromatosis type 1 (NF1) complicated by severe pulmonary aterial hypertension (PAH); only seven cases have been reported on this association so far, and PAH seems to be related to the vascular involvement of neurofibromatosis.

Essay A case of cerebrovascular accident.

diabetes, obesity, a sedentary lifestyle, and an elevated serum cholesterol level. Risk factors for hemorrhagic stroke include intracranial vascular anomalies, hypertension, family history, polycystic kidney disease, systemic lupus erythematosus, neurofibromatosis, Pregnancy, cigarette smoking.

Essay on Neurofibromatosis Neurofibromatosis My disorder research paper is about neurofibromatosis, which is a genetically-inherited disorder in which the nerve tissue grows tumors that may cause serious damage by compressing nerves and other tissues. Below is an essay on "Neurofibromatosis - Type 1" from Anti Essays, your source for research papers, essays, and term paper examples.

Neurofibromatosis – Type 1 Neurofibromatosis Type 1, also known as NF1 is an inherited disease that affects the skin, vision, and the neuroectodermal system. Neurofibromatosis Essay - Neurofibromatosis Neurofibromatosis is a disorder affecting the chromosomes of the human body.

It is .

Neurofibromatosis case essay
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