Some mutations could be heritable, Amyotrophic lateral scierosis essay from your parents genes. You are diagnosed with amyotrophic lateral sclerosis ALSa neurodegenerative disease that causes degeneration throughout the brain and spinal cord.
This is obviously a surgical procedure. ALS is a fatal disorder that causes progressive muscle paralysis. Using different BAC C9orf72 transgenic mouse model, they were able to study the symptoms of ALS, such as gait abnormalities, anxiety-like behavior, reduced grip strength, and even death rates .
Other NINDS-supported research studies are working to identify additional genes that may cause or put a person at risk for either familial or sporadic ALS. This means that everyone has the probability that they could get a genetic disorder.
Once scientists are capable of cloning specific types Amyotrophic lateral scierosis essay cells, such us nerve cells, cardiac cells, etc. In all cases the disease spreads and affects other regions.
Scientists and doctors have still not been able to find a permanent treatment for it. Men are slightly more likely than women to develop ALS. People that live with ALS every day.
Symptoms of lower motor neuron degeneration Amyotrophic lateral scierosis essay muscle weakness and atrophy, muscle cramps, and fleeting twitches of muscles that can be seen under the skin fasciculations although twitching is not a diagnostic symptom and more of a side effect so twitching would either occur after or accompany weakness and atrophy.
For more information abuot finding clinical trials on ALS, visit www. Several theories have been introduced over the years to try to explain ALS. Currently, as above stated, there is no cure for this disease.
The animal models can be C. Pathophysiology The pathogenesis is unclear, but there are three general types of ALS: Since then, more than a dozen additional genetic mutations have been identified, many through NINDS-supported research, and each of these gene discoveries is providing new insights into possible mechanisms of ALS.
There may be difficulty in swallowing and loss of tongue mobility. Affected individuals also face an increased risk of pneumonia during later stages of the disease. Stem cell research and therapeutic cloning, with all of the ethical issues they entail, have the potential of producing a cure for this only partially understood disease.
Adverse reactions during trials included nausea, dizziness, decreased lung function, diarrhea, abdominal pain, pneumonia, vomiting, vertigo, circumoral parathesis, anorexia, and somnolence.
As mentioned previously, the victims sometimes have to be fed through a tube because they are unable to chew. However, invasive ventilation imposes a heavy burden on caregivers and may decrease their quality of life. They are usually taken care of by a family member or even a close friend. Amitriptyline Elavildoxepin Sinequanand imipramine Tofranil have similar effects in providing antidepressant and antisialorrheic actions and provide nocturnal sedation, help potentiate analgesia and possible weight gain.
This form is called "bulbar onset".
Where can I get more information? Most people eventually are not able to walk or use their hands and arms, lose the ability to speak and swallow food and their own saliva, and begin to lose the ability to cough and to breathe on their own.
The parts of the body affected by early symptoms of ALS depend on which motor neurons in the body are damaged first. Riluzole is believed to reduce damage to motor neurons by decreasing levels of glutamate, which transports messages between nerve cells and motor neurons.
Some studies suggest that military veterans are about 1. It was just after his 21 birthday when he found out something was wrong. These motor neurons initiate and provide vital communication links between the brain and the voluntary muscles. Living with ALS is a very hard thing to do.
Or if arm-onset, difficulty with tasks requiring manual dexterity such as buttoning a shirt, writing, or turning a key in a lock may be experienced. Biomarkers can be molecules derived from a bodily fluid such as those in the blood and cerebrospinal fluidan image of the brain or spinal cord, or a measure of the ability of a nerve or muscle to process electrical signals.
Walling, Painful muscle cramps can be treated with nonsteroidal anti-inflammatory agents and anticonvulsive medications including carbamazepine Tegretol dose up to mg three times a day, or phenytoin Dilantin mg at bedtime.
A review concluded that smoking was an established risk factor for ALS. In the case of ALS, scientists could grow the specifically needed motor-neuron cells and inject or implant them into the ALS patient, replacing the faulty cells with healthy, normally functioning cells.
How Can I Help Research? The possibilities of therapeutic cloning and cell replacement technology are limitless as to what miracles they could produce in the medical field.
In the case of ALS, scientists could grow the specifically needed motor-neuron cells and inject or implant them into the ALS patient, replacing the faulty cells with healthy, normally functioning cells.Read Amyotrophic Lateral Sclerosis free essay and over 88, other research documents.
Amyotrophic Lateral Sclerosis. One day youвЂ™re a vibrant, healthy young individual. The next day, you find out you have a rare, currently untreatable. Research on amyotrophic lateral sclerosis has focused on animal models of the disease, its mechanisms, ways to diagnose and track it, and treatments.
Essay about Amyotrophic Lateral Sclerosis Words | 7 Pages. Amyotrophic Lateral Sclerosis is a motor neuron type disease.
The disease was first discovered in by French neurologist Jean-Martin Charcot. Amyotrophic lateral sclerosis, also known as Lou Gehrig’s disease, is a genetic disorder that occurs in the nervous system.
Each word in ALS briefly describes what the disorder is. Amyotrophic has two parts to it. Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND), or Lou Gehrig's disease, is a specific disease which causes the death of neurons controlling voluntary muscles.
Some also use the term motor neuron disease for a group of conditions of which ALS is the most common. ALS is. Amyotrophic lateral sclerosis or Lou Gehrig’s disease is a progressive disease that attacks motor neurons, components of the nervous system that connect the brain with the skeletal muscles, or voluntary muscles.Download